APPLICATION OF NUCLEAR MAGNETIC RESONANCE (NMR) AND MASS SPECTROMETRY IN IDENTIFICATION OF CHEMICAL COMPOUNDS

Abstract

This article provides a comprehensive analysis of the theoretical foundations of nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS), two advanced spectroscopic technologies widely used in determining the molecular structure and characteristics of chemical compounds. NMR spectroscopy provides detailed information about interatomic bonds, configuration, and conformations through the response of the nuclear environment in a molecule to electromagnetic resonance. MS technology allows for the identification of structural components of a compound through high-precision measurement of molecular mass and fragmentation analysis. The article justifies the use of these methods not only theoretically, but also in practical areas such as pharmaceuticals, organic synthesis, bioanalytics, and environmental monitoring. Current research conducted in Uzbekistan and the international scientific community, existing technological capabilities in national laboratories, and promising areas are also discussed. The results of the analysis show that the combined use of NMR and MS technologies dramatically increases the efficiency of complex analysis and ensures the highest level of reliability in the identification of chemical compounds.